이온빔 보조 전자빔 수산화 인회석 증착이 골내 임플란트의 골유착에 미치는 영향
EFFECTS OF THE ION BEAM ASSISTED DEPOSITION OF HYDROXYAPATITE ON OSSEOINTEGRATION OF THE ENDOSSEOUS IMPLANTS IN RABBIT TIBIAE
정영철, 한종현, 이인섭, 이현정, 김명호,
소속 상세정보
정영철 ( Jung Young-Chul ) - 연세대학교 치과대학 치과보철학교실
한종현 ( Han Chong-Hyun ) - 연세대학교 치과대학 치과보철학교실
이인섭 ( ) - 서울대학교 공과대학 재료공학부
이현정 ( Lee Hyun-Jung ) - 연세대학교 치과대학 구강생물학교실
김명호 ( Kim Myung-Ho ) - (주)우리동명 치과재료연구소
KMID : 0362420000380050659
Abstract
A large increase in the use of thin film coating of hydroxyapatite(HA) in implant dentistry is driven by the desire to take advantage of the excellent biocompatibility and high strength of HA coating. The purpose of this study was to evaluate the effects of HA-coated implants by Ion Beam Assisted Deposition(IBAD) method in comparison to the sand-blasted and machined surfaces. Osteoblast culture test, removal torque test and histomorphometric analysis were performed and the following results obtained;1. Examination of the osteoblast cultures displayed no difference in the secretion of alkaline phosphatase between the various specimen, but IBAD with pure HA specimen showed low alkaline phosphatase secretion(p<0.05).2. Removal torque tests showed HA-coated implants by IBAD method to be similar in high value to the implants with sand-blasted surface than the implants with machined surface. And the ovariectomized group showed low mechanical test value than the normal group(p<0.05).3. Histomorphometrical comparisons were performed on undecalcified ground sections. HA-coated implants by IBAD method demonstrated the highest mean bone-to-metal contact ratio on all threads and 3-best consecutive threads, and the implants with sand-blasted surface and implants with machined surface was in the next consecutive order(p<0.05). HA-coated implants showed slightly higher bone-to- metal contact ratio than sand-blasted implants, but no statistically significant difference was obtained between the two materials. The ovariectomized group showed lower value of bone-to-metal contact ratio than the normal group, but no statistically significant difference was obtained between the two groups.4. Evaluation of bone volume on all threads and 3-best consecutive threads showed no statistically significant difference among the different surface treatment groups, but showed lower bone volume in ovariectomized group than in the normal group(p<0.05).According to these results, thin film coated implants with HA showed high bone contact ratio, bone volume and removal torque strength in the short term, but long term observation is needed.
키워드
Implant;IBAD;Hydroxyapatite;Osteoblast;Alkaline phosphatase;Ovariectomy;Histomorphometry;Removal torque
원문 및 링크아웃 정보
등재저널 정보